I've watched a couple of riders, one a regular Advanced Group guy on an old type 750 and the other an instructor on the newer type frame 750. Both are faster than most liter bikes on tighter tracks and generally run with the "motard trains" . The instructor type was getting faster lap times at Talledega GP than he was on his 999. These two guys run about eqaul to each other on the Monsters, so I figure there is no significance difference in the frame types. Any real differences won't show up until you are running into what would be qualifying times to make the cut in AMA or Expert level races.
The newer frames are stiffer, but 10 lbs heavier. The hoop style suspension provides a more ridgid swingarm via it's 3 point support. How any of this translates into 'faster, safer, etc.", is open to debate.