Depends on your depth of experience and how easy you can reprogram your mind.
I'm with Scott and Chaf on this one. I've been riding with a conventional "1 down - 4 or 5 up" pattern for 26 years, I can't reprogram my brain now. I could probably do it for normal riding, but in an emergency situation lots of riding tasks go into autopilot, and that'd make a bad situation worse.
Not slagging the concept of the "reverse" pattern, it's probably better for the street, and is certainly better for racing.