It's a big step from a 400 Ninja for sure but if you've been tracking you should be OK. My guess is it'll take you a while to stop hitting the rev limiter!
The ergonomics are good for me. I have arthritis in my back and a herniated disc (I'm 74 and almost completely worn out) so the slightly forward lean is actually good for my back. It'll be pretty relaxed compared to a track bike. Respect the torque and learn to use it and the riding experience will be outstanding! Also respect the bike. She needs TLC and maintenance can be challenging and/or expensive. I'm a mechanical engineer, former flat tracker and bike shop owner, and a matter tech so I do all my own maintenance except machine work (cylinder boring, valve seat installation, etc) so I Sabre $1-2K a year I figure.
Welcome to Ducati-land. Glad to have you. You'll love it!